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Whether colchicine pretreatment or some other intervention directed at the pressure-stimulated signaling pathway regulating cancer cell adhesion could also reduce perioperative tumor adhesion and metastasis via the lymphatics and portal venous system awaits further study.

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Plant breeders have long used colchicine in the development of new plant cultivars.

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The wisdom of granting periods of marketing exclusivity to the maker of colcrys, the sole approved form of colchicine, was debated in the letters section of the oct.

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